Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28003534 | 0.80 | CTSV (0.38) | POLBALDH1A1LMNACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6155158 | 0.80 | ALDH1A1 (0.47) | KMT2APOLBALDH1A1LMNAHSD17B10 | |
| Ethoxycarbonyl Group SCHEMBL27794731 | 0.75 | AKT1 (0.36) | ALDH1A1TSHRCYP2C9 | |
| Ethoxycarbonyl Group SCHEMBL28765700 | 0.74 | RAB9A (0.40) | KMT2APOLBALDH1A1CYP1A2CYP3A4 | |
| Ethoxycarbonyl Group SCHEMBL27884559 | 0.72 | KDM4E (0.31) | KDM4E | |
| Ethoxycarbonyl Group SCHEMBL27667512 | 0.72 | KDM4E (0.31) | KDM4E | |
| Ethoxycarbonyl Group SCHEMBL28264125 | 0.72 | SMN1; SMN2 (0.35) | KMT2AALDH1A1LMNATSHRMEN1 | |
| Ethylbenzene SCHEMBL27309269 | 0.71 | TP53 (0.58) | KMT2AALDH1A1LMNATSHRMEN1 | |
| Ethoxycarbonyl Group SCHEMBL27715619 | 0.71 | MEN1 (0.31) | KMT2AALDH1A1MEN1KDM4ERAB9A | |
| Ethoxycarbonyl Group SCHEMBL27770294 | 0.71 | KDM4E (0.30) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071504-A | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2018-12-21 | — | — | CN | disclosed |