Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 10/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824092 | 0.93 | SPHK1 (0.52) | SPHK1SPHK2HRH3MAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL2826431 | 0.89 | FFAR1 (0.55) | SPHK1SPHK2HRH3 | |
| SCHEMBL2822644 | 0.87 | OPRM1 (0.48) | SPHK1SPHK2HRH3MAOAMAOB | |
| SCHEMBL13887161 | 0.86 | FFAR1 (0.60) | SPHK1SPHK2HRH3 | |
| SCHEMBL2827471 | 0.83 | HRH3 (0.44) | SPHK1HRH3MAOAMAOB | |
| SCHEMBL2827661 | 0.83 | HRH3 (0.42) | SPHK1SPHK2HRH3MAOAMAOB | |
| SCHEMBL2824720 | 0.83 | HRH3 (0.42) | SPHK1SPHK2HRH3MAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL2824089 | 0.82 | FFAR1 (0.55) | SPHK1SPHK2HRH3LTA4HEPHX2 | |
| SCHEMBL2823889 | 0.79 | LTA4H (0.65) | HRH3NPC1RAB9ALTA4HEPHX2 | |
| SCHEMBL2827613 | 0.79 | LTA4H (0.53) | HRH3NPC1RAB9ALTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1731505-B1 | ALKOXYPHENYLPROPANOIC ACID DERIVATIVES | TAKEDA PHARMACEUTICAL (JP) | 2015-01-14 | — | — | EP | disclosed |
| EP-2253315-A1 | Alkoxyphenylpropanoic acid derivatives | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-7517910-B2 | Alkoxyphenylpropanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20070213364-A1 | Alkoxyphenylpropanoic Acid Derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1731505-A1 | ALKOXYPHENYLPROPANOIC ACID DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213364-A1 | Alkoxyphenylpropanoic Acid Derivatives | GPR119, FFAR1, GPR55 | SPHK1 839/4885SPHK2 1435/4885HRH3 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.