SCHEMBL21743573

SCHEMBL21743573

Brc1ccc2c(c1)Sc1ccccc1C2(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
SNCA P37840 2/20 0.32
LMNA P02545 2/20 0.32
BCHE P06276 3/20 0.31
SLC6A3 Q01959 2/20 0.31
PDK2 Q15119 1/20 0.31
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
MAOA P21397 1/20 0.31
CNR1 P21554 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16787352 0.90 OPRM1 (0.37) OPRM1OPRD1SNCALMNABCHE
SCHEMBL23696826 0.88 LMNA (0.36) OPRM1OPRD1SNCALMNABCHE
SCHEMBL23697049 0.87 BCHE (0.37) OPRM1OPRD1SNCALMNABCHE
SCHEMBL28267231 0.84 NOX1 (0.41) SNCALMNABCHESLC6A3MEN1
SCHEMBL22589624 0.83 PDK2 (0.41) OPRM1OPRD1SNCALMNABCHE
SCHEMBL23697268 0.82 NOX1 (0.38) OPRM1OPRD1PDK2NOX1
SCHEMBL25705121 0.82 ALDH1A1 (0.33) OPRM1OPRD1MEN1MAPTKMT2A
SCHEMBL23697261 0.81 GABRG2 (0.37) BCHESLC6A3MEN1MAPTKMT2A
SCHEMBL21743587 0.80 MEN1 (0.38) SNCALMNABCHESLC6A3PDK2
SCHEMBL23697271 0.80 ACHE (0.44) OPRM1LMNABCHESLC6A3PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020036313-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-20 WO disclosed