Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | SDHB | P21912 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28032854 | 0.80 | HCAR2 (0.40) | KDM4ESMN1; SMN2HCAR2LMNAKMT2A | |
| SCHEMBL10519534 | 0.72 | NOS3 (0.50) | NPC1KDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL28269313 | 0.72 | NPC1 (0.38) | NPC1KDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL31135000 | 0.71 | LOXL2 (0.36) | NPC1KDM4EHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL5022939 | 0.71 | CCR1 (0.44) | NPC1KDM4EHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL5017672 | 0.70 | BPTF (0.47) | NPC1KDM4EHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL21020091 | 0.68 | KDM4E (0.67) | NPC1KDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL8597269 | 0.67 | LMNA (0.42) | NPC1KDM4EHSD17B10GAASMN1; SMN2 | |
| SCHEMBL5017675 | 0.67 | LMNA (0.50) | NPC1HSD17B10ALKRAB9ALMNA | |
| SCHEMBL5022932 | 0.67 | MAPT (0.65) | NPC1KDM4EHSD17B10SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955459-B | Substituted indoles -5- amphyl and its treatment use | 南特知识产权控股有限责任公司 | 2019-02-01 | — | — | CN | disclosed |