Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13318454 | 0.80 | ALDH1A1 (0.66) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL19409875 | 0.75 | MAPT (0.61) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL11259763 | 0.75 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL1459772 | 0.70 | MAPT (1.00) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL39057 | 0.70 | MAPT (1.00) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL4688106 | 0.67 | NR1H2 (1.00) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL8467713 | 0.67 | MGLL (0.79) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL4603359 | 0.67 | MAPT (0.49) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL14318236 | 0.67 | KDM4E (0.49) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL24430116 | 0.67 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977524-B | A kind of synthetic method of phenanthro- furans and azoles | 扬州大学 | 2019-03-01 | — | — | CN | claimed |