Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364068 | 0.87 | POLB (0.60) | KDM4EDHODHALDH1A1HPGDHSD17B10 | |
| SCHEMBL28277826 | 0.84 | ACLY (0.55) | KDM4EDHODHALDH1A1HPGDHSD17B10 | |
| SCHEMBL28278349 | 0.82 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL28276373 | 0.82 | POLB (0.48) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL17344732 | 0.81 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDCYP3A4LMNA | |
| SCHEMBL27352376 | 0.80 | MEN1 (0.50) | KDM4EDHODHALDH1A1HPGDPOLB | |
| SCHEMBL16383670 | 0.79 | KDM4E (1.00) | KDM4EPOLBLMNACYP1A2KMT2A | |
| SCHEMBL28277843 | 0.78 | MEN1 (0.57) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL27493833 | 0.78 | JAK2 (0.48) | KDM4EALDH1A1GAAGSK3BKMT2A | |
| SCHEMBL3636604 | 0.77 | KMT2A (0.54) | KDM4EDHODHALDH1A1MAPTCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516963-A | A method of preparing 1,2- dihydro-(4H) -3,1- benzoxazin-4-one compound | 上海交通大学 | 2019-03-26 | — | — | CN | claimed |
| CN-109516963-A | A method of preparing 1,2- dihydro-(4H) -3,1- benzoxazin-4-one compound | 上海交通大学 | 2019-03-26 | — | — | CN | disclosed |