SCHEMBL28277409

SCHEMBL28277409

O=CC(=O)c1occ2c1CCCC2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28277344 0.75
SCHEMBL8254443 0.68 NLRP3 (0.35) ALDH1A1
SCHEMBL27771525 0.66 NQO1 (0.32) ALDH1A1
SCHEMBL13021606 0.62 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL28146191 0.62 ALDH1A1 (0.31) ALDH1A1
SCHEMBL27802011 0.60 ALDH1A1 (0.31) ALDH1A1
SCHEMBL28009648 0.60
SCHEMBL28105938 0.59
SCHEMBL8620985 0.58 ALDH1A1 (0.41) ALDH1A1
SCHEMBL13021603 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116731003-A N-phenylimine-containing derivative, and preparation method and application thereof 贵州大学 2023-09-12 CN disclosed
CN-109415345-A Broad spectrum influenza inhibitor based on pyridazinone 豪夫迈·罗氏有限公司 2019-03-01 CN disclosed