Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18493829 | 0.81 | BCAT1 (0.54) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9931127 | 0.78 | CCR2 (0.65) | — | |
| SCHEMBL29236234 | 0.76 | PTGES2 (0.43) | KDM4ESMN1; SMN2PKMPTPN1NPC1 | |
| SCHEMBL14612820 | 0.73 | ALDH1A1 (0.67) | KMT2AACLYALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4057326 | 0.72 | ALDH1A1 (0.65) | KMT2AACLYALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1649827 | 0.72 | CA2 (0.47) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL12376737 | 0.71 | HTR2B (0.62) | KMT2AACLYALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15629008 | 0.70 | ALDH1A1 (0.63) | KMT2AMEN1ACLYALDH1A1LMNA | |
| SCHEMBL2941161 | 0.70 | CA12 (0.69) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL23093355 | 0.69 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384754-A | A kind of preparation method of dronedarone hydrochloride | 新发药业有限公司 | 2019-02-26 | — | — | CN | disclosed |