Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424941 | 0.75 | KMT2A (0.55) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL181841 | 0.73 | ALDH1A1 (0.74) | MAPTALDH1A1MEN1POLBKMT2A | |
| Piperazine SCHEMBL28327330 | 0.68 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ATDP1CES2 | |
| SCHEMBL260930 | 0.67 | — | — | |
| SCHEMBL11353795 | 0.67 | ELANE (0.41) | ALDH1A1KMT2ATSHRHTTERCC5 | |
| SCHEMBL11357937 | 0.67 | CES2 (0.46) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL11344993 | 0.67 | DAO (0.48) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL15354269 | 0.66 | ALDH1A1 (1.00) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL19458027 | 0.66 | POLB (0.63) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL29061555 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336891-A | 5-(furans -2`- carbonyl) -2,3- dihydro -1H- pyrroles piperazine -7- carboxylic acid and its derivative | 山东省医学科学院药物研究所（山东省抗衰老研究中心、山东省新技术制药研究所） | 2019-02-15 | — | — | CN | disclosed |