Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2828013 | 0.95 | ALDH1A1 (0.36) | MAPTMCHR1ALDH1A1MLYCD | |
| SCHEMBL2825542 | 0.92 | KIF18A (0.35) | MCHR1ALDH1A1MEN1KMT2APDE4B | |
| SCHEMBL2824028 | 0.87 | FABP3 (0.43) | MAPTSMN1; SMN2GAANPSR1ALDH1A1 | |
| SCHEMBL2825677 | 0.86 | FABP3 (0.45) | MAPTSMN1; SMN2GAANPSR1ALDH1A1 | |
| SCHEMBL2821880 | 0.86 | FABP3 (0.45) | MAPTSMN1; SMN2GAANPSR1ALDH1A1 | |
| SCHEMBL2826514 | 0.85 | TACR1 (0.42) | MAPTSMN1; SMN2GAANPSR1POLB | |
| SCHEMBL2826068 | 0.85 | NPSR1 (0.43) | MAPTSMN1; SMN2GAANPSR1ALDH1A1 | |
| SCHEMBL2823196 | 0.82 | GAA (0.40) | MAPTSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL2821958 | 0.81 | FABP3 (0.43) | MAPTSMN1; SMN2NPC1RAB9AMCHR1 | |
| SCHEMBL2821151 | 0.80 | KIF18A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809605-B1 | QUINOLINES AS ALLOSTERIC ENHANCERS OF THE GABA-B RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-08-11 | — | — | EP | claimed |