Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19617094 | 0.85 | HDAC6 (0.59) | LMNAL3MBTL1HDAC6MAPTPOLB | |
| SCHEMBL15381492 | 0.77 | LMNA (0.50) | ALDH1A1HTTALOX15SLC40A1LMNA | |
| SCHEMBL11299959 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HTTALOX15EGLN1SLC40A1 | |
| SCHEMBL2951217 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HTTALOX15EGLN1SLC40A1 | |
| SCHEMBL28624165 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HTTALOX15EGLN1SLC40A1 | |
| SCHEMBL16125601 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HTTALOX15EGLN1SLC40A1 | |
| SCHEMBL19616631 | 0.74 | HDAC6 (0.73) | HTTLMNAL3MBTL1HDAC6MAPT | |
| SCHEMBL19616872 | 0.74 | HDAC6 (0.70) | ALDH1A1HTTALOX15EGLN1SLC40A1 | |
| SCHEMBL6011752 | 0.73 | NOTUM (0.61) | ALDH1A1LMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL28232973 | 0.73 | SLC40A1 (0.46) | HTTALOX15EGLN1SLC40A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563046-A | 6 inhibitor of histone deacetylase enzyme and application thereof | DCB-美国有限责任公司 | 2019-04-02 | — | — | CN | disclosed |