Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | LGMN | Q99538 | 2/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21671924 | 0.86 | ALDH1A1 (0.42) | GAAMAPTNCF1ALDH1A1KDM4E | |
| SCHEMBL20784370 | 0.85 | KDM4E (0.46) | GAAMAPTNCF1ALDH1A1KDM4E | |
| SCHEMBL18029065 | 0.77 | ATR (0.46) | MAPTNCF1ATRALDH1A1KDM4E | |
| SCHEMBL21794742 | 0.69 | PRKCI (0.46) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL923404 | 0.68 | MAPT (0.62) | GAAMAPTSMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL20784335 | 0.68 | KDM4E (0.41) | GAAMAPTNCF1ALDH1A1KDM4E | |
| SCHEMBL28285609 | 0.68 | KDM4E (0.41) | GAAMAPTNCF1ALDH1A1KDM4E | |
| SCHEMBL14280213 | 0.67 | LGMN (0.71) | GAAMAPTSMN1; SMN2NCF1LGMN | |
| SCHEMBL23277969 | 0.67 | IRAK4 (0.48) | GAAMAPTSMN1; SMN2NCF1LGMN | |
| SCHEMBL20784367 | 0.67 | HTR6 (0.41) | GAAMAPTNCF1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422754-A | Pyrazolo [3,4-d] pyrimidine -3- ketone derivatives, its pharmaceutical composition and application | 上海迪诺医药科技有限公司 | 2019-03-05 | — | — | CN | disclosed |