Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 4/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | TEC | P42680 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14058648 | 0.84 | KDM4E (0.42) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL1593722 | 0.79 | KDM4E (0.37) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL8754981 | 0.77 | KDM4E (0.47) | KDM4EGAAHSD17B10TSHRMAPT | |
| SCHEMBL3047788 | 0.76 | ALDH1A1 (0.34) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL4316249 | 0.75 | MAPK1 (0.36) | KDM4ESIRT3TDP1GAAHSD17B10 | |
| SCHEMBL28709397 | 0.75 | SIRT3 (0.36) | KDM4ESIRT3TDP1GAANNMT | |
| SCHEMBL8852216 | 0.73 | KDM4E (0.36) | KDM4EMAPTJAK3 | |
| SCHEMBL6591933 | 0.73 | SRD5A1 (0.47) | KDM4ESIRT3GAAMAPTSRD5A1 | |
| SCHEMBL16795486 | 0.72 | KDM4E (0.42) | KDM4EGAAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL354227 | 0.72 | SIRT3 (0.45) | KDM4ESIRT3TDP1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109576341-A | A kind of lead compound screening technique inhibiting grouper pathogenic vibrio | 海南省海洋与渔业科学院（海南省海洋开发规划设计研究院） | 2019-04-05 | — | — | CN | disclosed |