Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 10/20 | 0.36 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CD38 | P28907 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28284553 | 0.75 | KDM4E (0.36) | SIRT3TDP1NNMTALDH1A1KDM4E | |
| SCHEMBL354227 | 0.73 | SIRT3 (0.45) | SIRT3TDP1PARP1NNMTALDH1A1 | |
| SCHEMBL27701122 | 0.73 | NNMT (0.42) | SIRT3TDP1NNMTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1776795 | 0.71 | SIRT3 (0.44) | SIRT3TDP1PARP1NNMTALDH1A1 | |
| SCHEMBL25945251 | 0.71 | CD38 (0.49) | PARP1MAPK8KCNH2CD38CYP3A4 | |
| SCHEMBL26418195 | 0.71 | ALDH1A1 (0.35) | TDP1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4329498 | 0.71 | SIRT3 (0.40) | SIRT3TDP1PARP1NNMTKCNH2 | |
| SCHEMBL7458258 | 0.70 | NEU3 (0.39) | SIRT3TDP1NNMTALDH1A1KDM4E | |
| SCHEMBL7761691 | 0.70 | TDP1 (0.42) | SIRT3TDP1PARP1NNMTALDH1A1 | |
| SCHEMBL5354600 | 0.70 | ERN1 (0.43) | SIRT3TDP1NNMTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174290-A | Modulators of TREX1 | 星座制药公司 | 2022-03-11 | — | — | CN | disclosed |