SCHEMBL1014576

SCHEMBL1014576

CC(C)c1ccc(CON=O)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.57
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
NFE2L2 Q16236 1/20 0.43
NPC1 O15118 5/20 0.40
RAB9A P51151 5/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
TYR P14679 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
ALDH1A1 P00352 3/20 0.37
KMT2A Q03164 1/20 0.37
MAOA P21397 1/20 0.37
ACHE P22303 1/20 0.37
MAOB P27338 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
ALOX5 P09917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28286129 0.77 AGXT (0.52) IDO1NPC1RAB9APOLBL3MBTL1
SCHEMBL21447792 0.77 CYP3A4 (0.44) RAB9AL3MBTL1ALDH1A1KMT2AMAOA
SCHEMBL27856388 0.77 IDO1 (0.52) IDO1NPC1RAB9AL3MBTL1KMT2A
SCHEMBL11341386 0.76 IDO1 (0.68) IDO1RXRARXRBNFE2L2NPC1
SCHEMBL2293769 0.76 IDO1 (0.68) IDO1RXRARXRBNFE2L2NPC1
SCHEMBL873057 0.74 ALDH1A1 (0.60) IDO1RXRARXRBNFE2L2NPC1
SCHEMBL764954 0.74 IDO1 (0.65) IDO1RXRARXRBNFE2L2NPC1
SCHEMBL7566657 0.74 IDO1 (0.50) IDO1KDM4EL3MBTL1ALDH1A1KMT2A
SCHEMBL27646961 0.73 IDO1 (0.55) IDO1NPC1RAB9APOLBMAOB
SCHEMBL260335 0.72 IDO1 (0.63) IDO1RXRARXRBNFE2L2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 WO claimed
US-20110020251-A1 Ultraviolet-Absorbing Compounds AVOCA LLC 2011-01-27 US claimed
EP-4361342-A1 PERFUME COMPOSITION Kao Corporation (JP) 2024-05-01 EP disclosed
EP-3416729-B1 PRO-FRAGRANCE COMPOSITION AQDOT LTD (GB) 2023-09-20 EP disclosed
US-11674110-B2 Compositions containing lauryl methacrylate for malodor reduction and uses thereof AGILEX FLAVORS AND FRAGRANCES, INC (US) 2023-06-13 US disclosed
EP-3325707-B1 COMPOSITIONS FOR MALODOR REDUCTION AND USE THEREOF AGILEX FLAVORS & FRAGRANCES INC (US) 2021-09-29 EP disclosed
US-10695277-B2 Pro-fragrance composition AQDOT LIMITED (GB) 2020-06-30 US disclosed
US-20200087596-A1 COMPOSITIONS FOR MALODOR REDUCTION AND USES THEREOF Agilex Flavors and Fragrances, Inc. (US) 2020-03-19 US disclosed
CN-105264057-B Spice composition 花王株式会社 2019-04-05 CN disclosed
EP-2496682-B1 DELIVERY PARTICLE PROCTER & GAMBLE (US) 2019-03-20 EP disclosed
US-20190046426-A1 PRO-FRAGRANCE COMPOSITION AQDOT LIMITED (GB) 2019-02-14 US disclosed
US-8673272-B2 Ultraviolet-absorbing compounds ISP INVESTMENTS INC. (US) 2014-03-18 US disclosed
US-8637259-B1 Methods of identifying modulators of olfactory receptors involved in the perception of sweat carboxylic acids CHEMCOM S.A. (BE) 2014-01-28 US disclosed
US-20130336910-A1 OLFACTORY RECEPTORS INVOLVED IN THE PERCEPTION OF SWEAT CARBOXYLIC ACIDS AND THE USE THEREOF CHEMCOM S.A. (BE) 2013-12-19 US disclosed
US-8357649-B2 Delivery particle THE PROCTER & GAMBLE COMPANY (US) 2013-01-22 US disclosed
US-20110107524-A1 DELIVERY PARTICLE THE PROCTER & GAMBLE COMPANY 2011-05-12 US disclosed
US-20110020251-A1 Ultraviolet-Absorbing Compounds AVOCA LLC 2011-01-27 US disclosed
US-20080085251-A1 even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; RESONAC CORPORATION (JP) 2008-04-10 US disclosed
EP-1827370-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR Showa Denko K.K. (JP) 2007-09-05 EP disclosed
WO-2006068276-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR SHOWA DENKO K.K. (JP) 2006-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020251-A1 Ultraviolet-Absorbing Compounds UFM1, UHRF1, CUTA IDO1 704/4885RXRA 2486/4885RXRB 3101/4885
US-20190046426-A1 PRO-FRAGRANCE COMPOSITION COPS5, COPS8, CBR3 IDO1 2923/4885RXRA 3136/4885RXRB 3365/4885
US-20080085251-A1 even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; TST, CYSLTR1, CYSLTR2 IDO1 662/4885RXRA 1417/4885RXRB 1754/4885
US-10695277-B2 Pro-fragrance composition COPS5, COPS8, CBR3 IDO1 2923/4885RXRA 3136/4885RXRB 3365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.