Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115896 | 0.77 | KDM4E (0.58) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL8977246 | 0.77 | ALDH1A1 (0.70) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL12727456 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL6243745 | 0.75 | MAPT (0.60) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL2115751 | 0.75 | ALDH1A1 (0.78) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL31393152 | 0.74 | RAB9A (0.55) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL5469005 | 0.74 | KDM4E (0.61) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7191192 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL30032182 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL28063129 | 0.72 | KIF11 (0.70) | ALDH1A1KDM4EHSD17B10HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503556-A | Quinazoline -2,4- derovatives and its preparation method and application | 东莞东阳光科研发有限公司 | 2019-03-22 | — | — | CN | disclosed |