Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14596918 | 0.79 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL28286807 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL6981145 | 0.75 | HSD17B10 (0.74) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL29326420 | 0.73 | HSD17B10 (0.48) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL29326398 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL5009323 | 0.72 | KDM4E (0.56) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL29326500 | 0.72 | TNKS2 (0.60) | KDM4ETP53HTTGAA | |
| SCHEMBL27191918 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL23791555 | 0.70 | CTSV (0.46) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL6981288 | 0.70 | NPEPPS (0.56) | ALDH1A1KDM4EHPGDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539114-A | Process for the preparation of substituted quinazoline-2,4,-diones | HOECHST AG (DE) | 1996-07-23 | — | — | US | disclosed |