Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PNP | P00491 | 2/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584897 | 0.79 | ALDH1A1 (0.47) | HPGDALDH1A1CYP3A4KDM4EKMT2A | |
| SCHEMBL5272693 | 0.78 | ALDH1A1 (0.53) | HPGDALDH1A1CYP3A4KDM4EKMT2A | |
| SCHEMBL11125362 | 0.77 | ALDH1A1 (0.55) | HPGDALDH1A1CYP3A4KDM4EKMT2A | |
| SCHEMBL1032784 | 0.77 | HPGD (1.00) | HPGDALDH1A1CYP3A4KDM4EKMT2A | |
| SCHEMBL4164688 | 0.76 | ALDH1A1 (0.51) | HPGDALDH1A1CYP3A4KDM4EKMT2A | |
| SCHEMBL4098207 | 0.76 | MEN1 (0.53) | HPGDALDH1A1CYP3A4KDM4EKMT2A | |
| SCHEMBL1584775 | 0.76 | ALDH1A1 (0.51) | HPGDALDH1A1CYP3A4KDM4EKMT2A | |
| Ethylene SCHEMBL28028832 | 0.75 | KDM4E (0.51) | HPGDALDH1A1CYP3A4KDM4EKMT2A | |
| SCHEMBL11706155 | 0.75 | HPGD (0.71) | HPGDALDH1A1CYP3A4KDM4EKMT2A | |
| SCHEMBL15978138 | 0.75 | FPR1 (0.51) | HPGDALDH1A1CYP3A4KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641904-A | The sulphur imido acyl group purine ketone compound that 7- for treating and preventing virus infection replaces | 豪夫迈·罗氏有限公司 | 2019-04-16 | — | — | CN | disclosed |