Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032784 | 0.83 | HPGD (1.00) | HPGDALDH1A1CYP3A4KMT2AMTNR1A | |
| SCHEMBL28287325 | 0.75 | HPGD (0.63) | HPGDALDH1A1CYP3A4KMT2AL3MBTL1 | |
| SCHEMBL1944831 | 0.75 | ALDH1A1 (0.63) | HPGDALDH1A1CYP3A4KMT2AL3MBTL1 | |
| SCHEMBL1031237 | 0.71 | HPGD (0.73) | HPGDALDH1A1CYP3A4KMT2AL3MBTL1 | |
| SCHEMBL2337883 | 0.71 | HPGD (0.58) | HPGDALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL7679940 | 0.71 | ALDH1A1 (0.77) | HPGDALDH1A1CYP3A4KMT2AMTNR1A | |
| SCHEMBL7092322 | 0.71 | CYP3A4 (0.75) | HPGDALDH1A1CYP3A4KMT2AMTNR1A | |
| SCHEMBL5272693 | 0.70 | ALDH1A1 (0.53) | HPGDALDH1A1CYP3A4KMT2AL3MBTL1 | |
| SCHEMBL1945491 | 0.70 | KDM4E (0.66) | HPGDALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL2284398 | 0.70 | ALDH1A1 (0.53) | HPGDALDH1A1CYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052391-A | ENZYME INHIBITOR, ANTIINFLAMMATORY SEDATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-10-04 | — | — | US | disclosed |
| US-3959280-A | ENZYME INHIBITORS; ANTIINFLAMMATORY, SEDATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-05-25 | — | — | US | disclosed |