Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401131 | 0.87 | ACHE (0.50) | ACHETDP1GAAALDH1A1TSHR | |
| SCHEMBL235851 | 0.87 | ACHE (0.50) | ACHETDP1GAAALDH1A1TSHR | |
| SCHEMBL11390703 | 0.87 | ALDH1A1 (0.40) | ACHEALDH1A1TSHR | |
| SCHEMBL6912797 | 0.81 | ACHE (0.62) | ACHETDP1GAAALDH1A1TSHR | |
| SCHEMBL4401181 | 0.80 | ACHE (0.42) | ACHETDP1GAAALDH1A1CA1 | |
| SCHEMBL3289160 | 0.80 | ACHE (0.42) | ACHETDP1GAAALDH1A1CA1 | |
| SCHEMBL12283588 | 0.78 | ACHE (0.48) | ACHETDP1GAAALDH1A1TSHR | |
| SCHEMBL20198275 | 0.78 | ACHE (0.48) | ACHETDP1GAAALDH1A1TSHR | |
| SCHEMBL3289166 | 0.78 | ACHE (0.48) | ACHETDP1GAAALDH1A1TSHR | |
| SCHEMBL19500066 | 0.77 | RAPGEF4 (0.39) | ACHETDP1RAPGEF4GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535046-B | Preparation method of sulfoxide compound | 江南大学 | 2020-01-17 | — | — | CN | disclosed |
| CN-109535046-A | A kind of preparation method of sulfoxide compound | 江南大学 | 2019-03-29 | — | — | CN | disclosed |