Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28209158 | 0.80 | KIF11 (0.50) | MAOBNPY5RSCN2A | |
| SCHEMBL28210972 | 0.80 | NPY5R (0.42) | IDO1KMT2ANPY5RGRIN2BGRIN1 | |
| SCHEMBL4025464 | 0.77 | TGFBR1 (0.60) | CTSSIDO1KMOMAOBKDM4E | |
| SCHEMBL29979429 | 0.77 | TGFBR1 (0.60) | CTSSIDO1KMOMAOBKDM4E | |
| SCHEMBL27862933 | 0.77 | GABRG2 (0.48) | IDO1NOTUMKMOMAOBKDM4E | |
| SCHEMBL4033214 | 0.76 | TGFBR1 (0.59) | CTSSIDO1KMOMAOBKDM4E | |
| SCHEMBL28210975 | 0.76 | NPY5R (0.50) | CTSSNPY5RXDH | |
| SCHEMBL8740185 | 0.76 | IDO1 (0.51) | CTSSIDO1NOTUMKMOMAOB | |
| SCHEMBL10836184 | 0.76 | KDM4E (0.53) | CTSSIDO1NOTUMCNR2KMO | |
| SCHEMBL8740145 | 0.76 | IDO1 (0.51) | CTSSIDO1NOTUMCNR2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349119-B | Pterene pyridazine octadentate double platinum complex phosphorescent material and preparation method and application thereof | 南京邮电大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-110862350-B | Pterene pyridazine tetradentate platinum complex phosphorescent material and preparation method and application thereof | 南京邮电大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-111349119-A | Pterene pyridazine octadentate double platinum complex phosphorescent material and preparation method and application thereof | 南京邮电大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-110862350-A | Pterene pyridazine tetradentate platinum complex phosphorescent material and preparation method and application thereof | 南京邮电大学 | 2020-03-06 | — | — | CN | disclosed |
| CN-109678908-A | It is a kind of using pyridyl derivatives as bicyclic metal platinum (II) complex of ligand and its preparation method and application | 安徽工业大学 | 2019-04-26 | — | — | CN | disclosed |
| CN-107334767-B | A kind of application of pyridazinone compound in oncotherapy | 中国医学科学院医药生物技术研究所 | 2019-03-05 | — | — | CN | disclosed |
| CN-106061974-B | Maleimide derivatives as the conditioning agent of WNT approach | 新加坡科技研究局 | 2018-04-20 | — | — | CN | disclosed |
| CN-107334767-A | A kind of application of pyridazinone compound in oncotherapy | 中国医学科学院医药生物技术研究所 | 2017-11-10 | — | — | CN | disclosed |
| CN-103772352-B | Pyridazinone derivatives and preparation method and application thereof | 四川百利药业有限责任公司 | 2017-01-18 | — | — | CN | disclosed |