Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542327 | 0.74 | MAPT (0.42) | MAPTMT-CO2LMNAKMT2AMEN1 | |
| SCHEMBL6944649 | 0.73 | MAOB (0.48) | MAPTLMNAKMT2AMEN1IDO1 | |
| SCHEMBL28053382 | 0.71 | — | — | |
| SCHEMBL3828871 | 0.71 | — | — | |
| SCHEMBL11175497 | 0.71 | GAA (0.49) | MAPTLMNAKMT2AMEN1IDO1 | |
| SCHEMBL8830220 | 0.71 | ALOX12 (0.41) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL5545978 | 0.69 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EHPGDMAPK1 | |
| SCHEMBL1686571 | 0.68 | LMNA (0.57) | MAPTMT-CO2LMNAKMT2AMEN1 | |
| SCHEMBL9516529 | 0.68 | LMNA (0.57) | MAPTMT-CO2LMNAKMT2AMEN1 | |
| SCHEMBL5542524 | 0.68 | TSHR (0.46) | MAPTLMNAKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761880-A | The synthetic method of Carprofen and its intermediate | 王美妮 | 2019-05-17 | — | — | CN | disclosed |
| CN-109761881-A | The synthetic method of Carprofen and its intermediate | 王美妮 | 2019-05-17 | — | — | CN | disclosed |
| CN-109705020-A | The synthetic method of Carprofen and its intermediate | 王美妮 | 2019-05-03 | — | — | CN | disclosed |