Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 3/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193196 | 0.81 | FABP4 (0.47) | FABP4LDHAALDH1A1MYCDHODH | |
| SCHEMBL11667831 | 0.79 | FABP4 (0.49) | FABP4LDHAALDH1A1MYCDHODH | |
| SCHEMBL3825797 | 0.77 | FABP4 (0.48) | FABP4LDHAALDH1A1MYCKDM4E | |
| SCHEMBL28575871 | 0.75 | KDM4E (0.49) | FABP4LDHAALDH1A1DHODHKDM4E | |
| SCHEMBL28415304 | 0.74 | ALDH1A1 (0.45) | FABP4LDHAALDH1A1MYCKDM4E | |
| SCHEMBL28589329 | 0.73 | AKR1C2 (0.46) | FABP4ALDH1A1DHODHMCL1HNF4A | |
| SCHEMBL28583832 | 0.73 | GPR35 (0.47) | LDHAALDH1A1DHODHKDM4EMEN1 | |
| SCHEMBL11586143 | 0.72 | ALDH1A1 (0.47) | FABP4LDHAALDH1A1MYCKMT2A | |
| SCHEMBL30753447 | 0.72 | ALDH1A1 (0.47) | FABP4LDHAALDH1A1MYCKDM4E | |
| SCHEMBL14784538 | 0.72 | PTPN1 (0.53) | LDHADHODHMCL1HNF4AACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665958-B | Method for preparing polysubstituted 1-naphthoic acid compound under catalysis of ruthenium | 广州大学 | 2021-05-11 | — | — | CN | disclosed |
| CN-109665958-A | A kind of method that ruthenium catalysis prepares polysubstituted 1- naphthoic acid class compound | 广州大学 | 2019-04-23 | — | — | CN | disclosed |