Malonic Acid

Malonic Acid

SCHEMBL28290691

CCCCC(O)O.O=C(O)CC(=O)O

nearest known ligand 0.47

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 8/20 0.47
CA2 P00918 3/20 0.46
MAPK1 P28482 1/20 0.46
FFAR1 O14842 2/20 0.45
FFAR4 Q5NUL3 1/20 0.45
LDHA P00338 1/20 0.43
SRR Q9GZT4 1/20 0.43
AKR1B1 P15121 1/20 0.42
CA1 P00915 2/20 0.42
PLA2G2C Q5R387 1/20 0.42
ACHE P22303 1/20 0.41
BACE1 P56817 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL30377870 0.93 GPR84 (0.55) GPR84FFAR1FFAR4AKR1B1ALDH1A1
Acetoacetic Acid SCHEMBL9681644 0.89 GPR84 (0.42) GPR84CA2MAPK1FFAR1FFAR4
Acetoacetic Acid SCHEMBL9680475 0.89 GPR84 (0.42) GPR84CA2MAPK1FFAR1FFAR4
Propionic Acid SCHEMBL27488815 0.88 FFAR3 (0.50) GPR84CA2MAPK1FFAR1FFAR4
Succinic Acid SCHEMBL28075979 0.86 FFAR4 (0.55) GPR84FFAR1FFAR4AKR1B1ALDH1A1
Malonic Acid SCHEMBL28697215 0.85 LDHA (0.47) GPR84FFAR1FFAR4LDHASRR
Acetic Acid SCHEMBL27447217 0.85 CA2 (0.50) GPR84CA2MAPK1FFAR1FFAR4
Oxalic Acid SCHEMBL31135505 0.85 CA2 (0.50) GPR84CA2MAPK1FFAR1FFAR4
Itaconate SCHEMBL28809363 0.84 ALOX15 (0.47) GPR84CA2MAPK1FFAR1FFAR4
Adipic Acid SCHEMBL23795032 0.84 AKR1B1 (0.65) GPR84FFAR1FFAR4AKR1B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791381-A Electrophotographic photoreceptor, and electrophotographic process cartridge and image forming apparatus containing the same 三菱化学株式会社 2019-05-21 CN disclosed