Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | DCK | P27707 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HEXA | P06865 | 1/20 | 0.44 |
| ▸ | HEXB | P07686 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398630 | 0.89 | ALOX5 (0.49) | HRH3ALOX5DCKPTGDR2ALDH1A1 | |
| SCHEMBL12321744 | 0.83 | RAB9A (0.54) | HRH3ALOX5ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18015850 | 0.82 | L3MBTL1 (0.55) | HRH3DCKPTGDR2ALDH1A1KDM4E | |
| SCHEMBL16398461 | 0.78 | MAPT (0.43) | HRH3ALOX5PTGDR2ALDH1A1CYP1A2 | |
| SCHEMBL16399629 | 0.78 | HRH3 (0.45) | HRH3ALOX5PTGDR2ALDH1A1CYP1A2 | |
| SCHEMBL28292288 | 0.78 | AGER (0.53) | HRH3ALOX5HTT | |
| SCHEMBL6503373 | 0.76 | L3MBTL1 (0.57) | HRH3ALOX5PTGDR2ALDH1A1CYP1A2 | |
| SCHEMBL16399784 | 0.76 | HTT (0.50) | ALOX5DCKPTGDR2ALDH1A1CYP1A2 | |
| SCHEMBL12344791 | 0.76 | RAB9A (0.67) | PTGDR2ALDH1A1CYP1A2CYP2C9KDM4E | |
| SCHEMBL12475538 | 0.73 | PTPN11 (0.60) | ALOX5PTGDR2ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383068-B | Thiazole and triazole -6- acetamide derivative and application | 石家庄学院 | 2019-05-10 | — | — | CN | disclosed |