Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | OGG1 | O15527 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12137517 | 0.79 | NR1H2 (0.56) | SMN1; SMN2MAPTHSD17B10HTTMEN1 | |
| SCHEMBL3375733 | 0.75 | MAPT (0.51) | SMN1; SMN2MAPTTSHRHTTMEN1 | |
| SCHEMBL30938682 | 0.74 | MAPT (0.62) | SMN1; SMN2MAPTTSHRHTTMEN1 | |
| SCHEMBL2581844 | 0.74 | MAPT (0.62) | SMN1; SMN2MAPTTSHRHTTMEN1 | |
| SCHEMBL3373042 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTTSHRHTTMEN1 | |
| SCHEMBL12763220 | 0.74 | TSHR (0.53) | SMN1; SMN2MAPTTSHRHTTMEN1 | |
| SCHEMBL11604607 | 0.74 | ALDH1A1 (0.76) | SMN1; SMN2MAPTHTTMEN1KMT2A | |
| SCHEMBL3123013 | 0.73 | LMNA (0.60) | SMN1; SMN2MAPTTSHRHTTLMNA | |
| SCHEMBL15805460 | 0.73 | MAPT (0.51) | SMN1; SMN2MAPTTSHRHTTMEN1 | |
| SCHEMBL15805310 | 0.72 | L3MBTL1 (0.52) | SMN1; SMN2MAPTTSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866484-B | A method of preparing pyrroles, imidazoles, oxazole derivatives | 中国科学院大连化学物理研究所 | 2019-04-09 | — | — | CN | disclosed |