Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 9/20 | 0.49 |
| ▸ | DAGLA | Q9Y4D2 | 9/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | OGT | O15294 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27824322 | 0.77 | DAGLA (0.54) | ABHD6DAGLAMEN1CASP3KMT2A | |
| SCHEMBL28070960 | 0.75 | DRD2 (0.53) | ABHD6GRM5GRM1GPR119 | |
| SCHEMBL25445548 | 0.75 | ROCK2 (0.56) | SCDCKS1BSKP1SKP2GPR119 | |
| SCHEMBL28135749 | 0.74 | DAGLA (0.52) | ABHD6DAGLAOGTMEN1CASP3 | |
| SCHEMBL27647927 | 0.73 | GPR119 (0.49) | SCDBRD9CKS1BSKP1SKP2 | |
| SCHEMBL25736849 | 0.73 | FAAH (0.40) | GRM5GRM1SCDHTTATM | |
| SCHEMBL13425969 | 0.72 | SCD (0.42) | SCDBRD9CKS1BSKP1SKP2 | |
| SCHEMBL25231486 | 0.72 | SCD (0.42) | SCDBRD9CKS1BSKP1SKP2 | |
| SCHEMBL31300251 | 0.72 | DAGLA (0.37) | ABHD6DAGLA | |
| SCHEMBL28290881 | 0.72 | DAGLA (0.47) | ABHD6DAGLAMEN1CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646492-B | Substituted xanthine class compound and its preparation method and application containing five yuan of heteroaromatics | 中国医学科学院药物研究所 | 2019-04-09 | — | — | CN | disclosed |