Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920680 | 0.85 | ALDH1A1 (0.49) | L3MBTL1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL2321965 | 0.85 | ACHE (0.67) | ACHEEPHX1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7428185 | 0.84 | MAPT (0.56) | ACHEL3MBTL3L3MBTL1EPHX1SMN1; SMN2 | |
| SCHEMBL1298628 | 0.82 | HPGD (0.59) | L3MBTL3L3MBTL1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL1921183 | 0.82 | HPGD (0.55) | SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL27991527 | 0.81 | L3MBTL3 (0.66) | ACHEL3MBTL3L3MBTL1EPHX1PARP1 | |
| SCHEMBL1298971 | 0.81 | HPGD (0.62) | L3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL27842179 | 0.81 | L3MBTL3 (0.47) | ACHEL3MBTL3L3MBTL1EPHX1KDM1A | |
| SCHEMBL409005 | 0.80 | ACHE (0.69) | ACHEL3MBTL3L3MBTL1EPHX1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4618202 | 0.79 | ACHE (0.67) | ACHEL3MBTL3L3MBTL1EPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104350055-B | Bicyclic heteroaryl derivatives and application thereof as MNK1 and MNK2 regulator | 新加坡科技研究局 | 2019-05-31 | — | — | CN | disclosed |