Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920680 | 0.85 | ALDH1A1 (0.49) | HPGDALDH1A1TP53CA12CA1 | |
| SCHEMBL28291402 | 0.85 | ACHE (0.46) | ACHEHPGDKMT2ASMN1; SMN2EPHX1 | |
| SCHEMBL27991527 | 0.84 | L3MBTL3 (0.66) | ACHEEPHX1 | |
| SCHEMBL7428185 | 0.84 | MAPT (0.56) | ACHENPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1921183 | 0.82 | HPGD (0.55) | HPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1298628 | 0.82 | HPGD (0.59) | HPGDALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL1298702 | 0.81 | POLB (0.54) | NPC1HPGDGRM5KMT2ATSHR | |
| SCHEMBL7002476 | 0.81 | HSP90AA1 (0.44) | ACHEHPGDALDH1A1TP53KMT2A | |
| SCHEMBL28292825 | 0.81 | L3MBTL3 (0.59) | ALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1298971 | 0.81 | HPGD (0.62) | HPGDALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |