Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991292 | 0.79 | L3MBTL1 (0.49) | HPGDALDH1A1L3MBTL1ALOX15LMNA | |
| SCHEMBL5497829 | 0.77 | HSP90AA1 (0.50) | HPGDALDH1A1L3MBTL1ALOX15LMNA | |
| SCHEMBL182953 | 0.77 | ALDH1A1 (0.54) | HPGDALDH1A1L3MBTL1ALOX15LMNA | |
| SCHEMBL4319075 | 0.75 | ALDH1A1 (0.46) | HPGDALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL16463399 | 0.75 | L3MBTL1 (0.48) | HPGDALDH1A1L3MBTL1ALOX15LMNA | |
| SCHEMBL28292798 | 0.74 | L3MBTL1 (0.48) | HPGDALDH1A1L3MBTL1ALOX15LMNA | |
| SCHEMBL4286287 | 0.73 | IRAK4 (0.42) | ALDH1A1LMNATSHRPOLBKDM4E | |
| SCHEMBL27991513 | 0.72 | L3MBTL1 (0.48) | HPGDALDH1A1L3MBTL1ALOX15LMNA | |
| SCHEMBL3891455 | 0.71 | DRD2 (0.44) | ALDH1A1L3MBTL1KMT2AGAAKDM4E | |
| SCHEMBL17502622 | 0.69 | HTT (0.63) | TSHRKMT2AHTTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104350055-B | Bicyclic heteroaryl derivatives and application thereof as MNK1 and MNK2 regulator | 新加坡科技研究局 | 2019-05-31 | — | — | CN | disclosed |