Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25918159 | 0.89 | NPSR1 (0.70) | NPSR1APPNPC1RAB9AVCP | |
| SCHEMBL28290036 | 0.84 | NPSR1 (0.60) | NPSR1NPC1RAB9AMAPTVCP | |
| SCHEMBL28290037 | 0.82 | NPSR1 (0.57) | NPSR1APPNPC1RAB9AMAPT | |
| SCHEMBL28291465 | 0.80 | NPSR1 (0.54) | NPSR1NPC1RAB9AMAPTPOLB | |
| SCHEMBL22079525 | 0.79 | NPSR1 (0.57) | NPSR1NPC1RAB9AMAPTVCP | |
| SCHEMBL11636289 | 0.76 | NPSR1 (1.00) | NPSR1APPNPC1RAB9AMAPT | |
| SCHEMBL3859101 | 0.74 | MCHR1 (0.53) | NPSR1MAPTHTR2AHTR2CHTR2B | |
| SCHEMBL2095324 | 0.72 | GAA (0.44) | APPMAPTGAAPKMGPBAR1 | |
| SCHEMBL13284136 | 0.71 | VCP (0.69) | NPSR1APPGFERNPC1RAB9A | |
| SCHEMBL30369800 | 0.71 | NR1H3 (0.62) | NPC1RAB9AMAPTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107337663-B | A kind of preparation method of thio three ketene compound of loop coil of visible light-inducing 3- | 曲阜师范大学 | 2019-09-17 | — | — | CN | disclosed |
| CN-107141248-B | A kind of method of visible light catalytic synthesis three ketene compound of 3- sulfuryl loop coil | 曲阜师范大学 | 2019-04-30 | — | — | CN | disclosed |