Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 12/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872616 | 0.90 | MMP2 (0.48) | MTNR1AMTNR1BCHEK2MMP2MMP13 | |
| SCHEMBL28687273 | 0.87 | MTNR1A (0.43) | MTNR1AMTNR1BPLGPLAUHTR1A | |
| SCHEMBL28787309 | 0.81 | MTNR1A (0.36) | MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL27792587 | 0.78 | GAA (0.39) | MTNR1AMTNR1B | |
| SCHEMBL28291596 | 0.78 | MTNR1A (0.37) | MTNR1AMTNR1B | |
| SCHEMBL28658782 | 0.78 | DAO (0.42) | MTNR1AMTNR1B | |
| SCHEMBL27550869 | 0.78 | DAO (0.42) | MTNR1AMTNR1B | |
| SCHEMBL28072258 | 0.78 | MAPT (0.43) | MTNR1AMTNR1BMEN1CYP1A2TSHR | |
| SCHEMBL28819115 | 0.76 | MTNR1A (0.43) | MTNR1AMTNR1BMMP2MMP13HTR1A | |
| SCHEMBL27488329 | 0.76 | LOXL2 (0.50) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-A | A kind of synthetic method of 2- substituted indole derivative | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | disclosed |