Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329312 | 0.84 | CTSD (0.42) | CASP1SMN1; SMN2CTSDKMT2AMEN1 | |
| SCHEMBL7270150 | 0.84 | HTT (0.51) | CTSD | |
| SCHEMBL28291704 | 0.83 | HDAC1 (0.58) | ALOX5HDAC1HDAC2KMT2AALDH1A1 | |
| SCHEMBL7321477 | 0.82 | CASP1 (0.46) | CASP1CTSDKMT2AMEN1 | |
| SCHEMBL6452185 | 0.81 | CTSB (0.51) | CASP1CTSDKMT2AMEN1 | |
| SCHEMBL26616467 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2HDAC1HDAC2KMT2AALDH1A1 | |
| SCHEMBL7319638 | 0.81 | CTSK (0.46) | CASP1CTSD | |
| SCHEMBL27286594 | 0.80 | ANPEP (0.43) | SMN1; SMN2ALOX5MMP1MMP9MMP14 | |
| Hydrochloric Acid SCHEMBL7331042 | 0.80 | CASP1 (0.43) | CASP1SMN1; SMN2ALOX5HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL7325792 | 0.79 | CTSB (0.51) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594586-A4 | HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0594586-A1 | HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1991010442-A1 | HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-25 | — | — | WO | disclosed |