Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1237453 | 0.85 | KMT2A (0.42) | EGFRKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL3987325 | 0.83 | KMT2A (0.41) | EGFRKMT2AKDM4E | |
| Biphenyl SCHEMBL28688628 | 0.81 | MGLL (0.43) | MGLLEGFRKMT2ACYP2C19KDM4E | |
| SCHEMBL6590484 | 0.81 | HSD17B10 (0.42) | HDAC8 | |
| SCHEMBL22960747 | 0.80 | MGLL (0.62) | MGLLADORA3KAT6AHDAC8KMO | |
| SCHEMBL16472962 | 0.74 | MGLL (0.64) | MGLLHDAC8MEN1KMT2AKMO | |
| Biphenyl SCHEMBL27492413 | 0.73 | TSHR (0.52) | EGFRKMT2ACYP2C19KDM4E | |
| SCHEMBL29658033 | 0.73 | MGLL (0.62) | MGLLHDAC8KMO | |
| SCHEMBL5778129 | 0.72 | KMT2A (0.44) | KMT2AKDM4E | |
| SCHEMBL28664851 | 0.72 | TRPV6 (0.44) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715615-A | Biaryl methyl heterocycles | 蒙特利尔大学 | 2019-05-03 | — | — | CN | disclosed |