Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18980769 | 0.83 | LMNA (0.41) | HSD17B10SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL28291707 | 0.81 | MGLL (0.51) | HDAC8 | |
| SCHEMBL1237453 | 0.80 | KMT2A (0.42) | HSD17B10SMN1; SMN2RAB9AALDH1A1ENPP2 | |
| Hydrochloric Acid SCHEMBL3987325 | 0.79 | KMT2A (0.41) | HSD17B10SMN1; SMN2RAB9AALDH1A1ENPP2 | |
| SCHEMBL8297905 | 0.78 | ACHE (0.44) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL3985882 | 0.75 | ACHE (0.41) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL28687637 | 0.73 | ENPP2 (0.61) | SMN1; SMN2NPC1RAB9ATP53LMNA | |
| SCHEMBL28878253 | 0.73 | ACHE (0.42) | RELALMNAHDAC8HDAC6FAAH | |
| SCHEMBL22190325 | 0.73 | ACHE (0.42) | RELALMNAALDH1A1CYP3A4MAPK1 | |
| SCHEMBL2320318 | 0.73 | ACHE (0.42) | HSD17B10RELALMNAHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483236-A1 | AMINOALCOHOL DERIVATIVES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003076397-A1 | AMINOALCOHOL DERIVATIVES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | WO | disclosed |