SCHEMBL1237453

SCHEMBL1237453

COC(=O)OB(O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
ENPP2 Q13822 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
PCSK9 Q8NBP7 1/20 0.39
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39
TRPV6 Q9H1D0 1/20 0.39
CTRB1 P17538 2/20 0.39
KCNN4 O15554 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3987325 0.98 KMT2A (0.41) KMT2ATSHRHSD17B10KDM4EHPGD
SCHEMBL28664851 0.85 TRPV6 (0.44) TSHRCA4CA6CA5ACA7
SCHEMBL28291707 0.85 MGLL (0.51) KMT2AKDM4EEGFR
SCHEMBL5778129 0.82 KMT2A (0.44) KMT2ATSHRHSD17B10KDM4EHPGD
SCHEMBL6590484 0.80 HSD17B10 (0.42) HSD17B10ENPP2ALDH1A1RAB9ASMN1; SMN2
Biphenyl SCHEMBL28688628 0.80 MGLL (0.43) KMT2ATSHRHSD17B10KDM4EHPGD
SCHEMBL4763196 0.79 TSHR (0.38) KMT2ATSHRHSD17B10HPGDCA4
SCHEMBL1237692 0.79 TSHR (0.44) KMT2ATSHRHSD17B10ALDH1A1MAPT
SCHEMBL18424371 0.79 CYP2C19 (0.39) KMT2ATSHRHSD17B10CA4CA6
SCHEMBL651370 0.79 ORAI1 (0.42) TSHRHSD17B10KDM4EHPGDCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307822-A Production process of environment-friendly laminating material 广东美士达药包材料股份有限公司 2024-07-09 CN claimed
CN-117946029-A Organic molecule capable of emitting red light as well as preparation method and application thereof 中国科学院福建物质结构研究所 2024-04-30 CN claimed
CN-117534681-A Preparation and application of aromatic ester electrochromic material with spirodipropyl dioxythiophene as core 南京林业大学 2024-02-09 CN claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
CN-115433364-A Hydrogen bond organic molecular framework material HOF-NBDA and preparation method and application thereof 中国科学院福建物质结构研究所 2022-12-06 CN claimed
CN-111004149-B Method for preparing polyfluorobenzonitrile by catalytic fluorination of polychlorinated benzonitrile 大连奇凯医药科技有限公司 2022-06-07 CN claimed
CN-113354828-A Preparation and application of novel stable metal organic framework material 沈阳大学 2021-09-07 CN claimed
CN-112898583-A Preparation method and application of metal organic framework material 北京化工大学 2021-06-04 CN claimed
CN-112812320-A Preparation of nitrogen-substituted metal organic framework material and high-pressure methane storage application thereof 沈阳大学 2021-05-18 CN claimed
EP-2729184-A1 NOVEL AGONISTS AND ANTAGONISTS OF THE UROTENSINERGIC SYSTEM Institut National de la Recherche Scientifique (CA) 2014-05-14 EP claimed
WO-2012149644-A1 NOVEL AGONISTS AND ANTAGONISTS OF THE UROTENSINERGIC SYSTEM INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2012-11-08 WO claimed
US-12545640-B2 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof SANOFI (FR) 2026-02-10 US disclosed
CN-119751461-A PKMYT1 inhibitor and preparation method and application thereof 中国药科大学 2025-04-04 CN disclosed
WO-2025045826-A1 COMPOUNDS FOR ACTIVATION OF FGFR1 SIGNALING THE CULTIVATED B. GMBH (DE) 2025-03-06 WO disclosed
US-20240237529-A1 NOVEL COMPOUND, AND PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-11 US disclosed
WO-2005123680-A1 SIX-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2005-12-29 WO disclosed
WO-2005097740-A1 HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2005-10-20 WO disclosed
WO-2005042488-A1 PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-05-12 WO disclosed
EP-1503992-A1 PYRIDAZIN-3(2H)-ONE DERIVATIVES AS PDE4 INHIBITORS Almirall Prodesfarma, S.A. (ES) 2005-02-09 EP disclosed
WO-2003097613-A1 PYRIDAZIN-3(2H)-ONE DERIVATIVES AS PDE4 INHIBITORS ALMIRALL PRODESFARMA SA (ES) 2003-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545640-B2 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof ESRRA, GPER1, FSHR KMT2A 3398/4885TSHR 34/4885HSD17B10 211/4885
US-20240237529-A1 NOVEL COMPOUND, AND PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING SAME CRY1, NCS1, CYP4X1 KMT2A 968/4885TSHR 3853/4885HSD17B10 1064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.