Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17008795 | 0.83 | GPR6 (0.47) | GPR6 | |
| SCHEMBL223791 | 0.83 | GPR119 (0.64) | GPR6 | |
| SCHEMBL28101022 | 0.83 | FPR2 (0.49) | GPR6 | |
| SCHEMBL28072761 | 0.82 | GPR6 (0.48) | GPR6 | |
| SCHEMBL227139 | 0.81 | GPR6 (0.58) | GPR6 | |
| SCHEMBL21886989 | 0.80 | GPR119 (0.56) | GPR6 | |
| SCHEMBL227505 | 0.80 | HRH3 (0.61) | GPR6 | |
| SCHEMBL21824767 | 0.76 | USP30 (0.50) | GPR6 | |
| SCHEMBL27805795 | 0.76 | GPR119 (0.41) | GPR6 | |
| SCHEMBL23686797 | 0.75 | SLC6A9 (0.47) | GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103421-B | The pyrazine regulator of GPR6 | 武田药品工业株式会社 | 2019-04-09 | — | — | CN | disclosed |