Carbon Tetrachloride

Carbon Tetrachloride

SCHEMBL28292390

Cc1ccccc1S(C)(=O)=O.ClC(Cl)(Cl)Cl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
ALDH1A1 P00352 6/20 0.40
HSD11B1 P28845 2/20 0.40
RXFP1 Q9HBX9 1/20 0.40
MCL1 Q07820 1/20 0.39
RAPGEF4 Q8WZA2 1/20 0.39
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 2/20 0.38
TP53 P04637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.38
BCAT2 O15382 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28278788 0.91 L3MBTL1 (0.50) L3MBTL1ALDH1A1HSD11B1RXFP1RAPGEF4
SCHEMBL12307 0.91 L3MBTL1 (0.50) L3MBTL1ALDH1A1HSD11B1RXFP1RAPGEF4
Bromide SCHEMBL28167960 0.89 L3MBTL1 (0.48) L3MBTL1ALDH1A1HSD11B1RXFP1RAPGEF4
Chloroform SCHEMBL28290992 0.87 L3MBTL1 (0.44) L3MBTL1ALDH1A1HSD11B1RXFP1RAPGEF4
Cyanide SCHEMBL27700014 0.84 L3MBTL1 (0.45) L3MBTL1ALDH1A1HSD11B1RXFP1RAPGEF4
SCHEMBL28745645 0.78 ALDH1A1 (0.40) L3MBTL1ALDH1A1HSD11B1RXFP1MCL1
SCHEMBL8106699 0.75 LOX (0.47) L3MBTL1ALDH1A1HSD11B1LMNAHTT
SCHEMBL4439 0.75 ALDH1A1 (0.44) L3MBTL1ALDH1A1HSD11B1RXFP1RAPGEF4
SCHEMBL30950298 0.75 ALDH1A1 (0.44) L3MBTL1ALDH1A1HSD11B1RXFP1RAPGEF4
SCHEMBL28650941 0.74 HSD11B1 (0.40) L3MBTL1ALDH1A1HSD11B1RXFP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106957250-B A kind of bromination process of pair of methylsulfonyltoluene 湖北君尚科技有限公司 2019-04-09 CN disclosed