Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12307 | 0.93 | L3MBTL1 (0.50) | L3MBTL1RAPGEF4TSHRACHEALDH1A1 | |
| SCHEMBL28278788 | 0.93 | L3MBTL1 (0.50) | L3MBTL1RAPGEF4TSHRACHEALDH1A1 | |
| Bromide SCHEMBL28167960 | 0.91 | L3MBTL1 (0.48) | L3MBTL1RAPGEF4TSHRACHEALDH1A1 | |
| Chloroform SCHEMBL28290992 | 0.84 | L3MBTL1 (0.44) | L3MBTL1RAPGEF4TSHRACHEALDH1A1 | |
| Carbon Tetrachloride SCHEMBL28292390 | 0.84 | L3MBTL1 (0.44) | L3MBTL1RAPGEF4TSHRACHEALDH1A1 | |
| SCHEMBL8106699 | 0.77 | LOX (0.47) | L3MBTL1ALDH1A1KDM4ETP53BCAT2 | |
| SCHEMBL3800751 | 0.76 | TSHR (0.43) | L3MBTL1RAPGEF4TSHRACHEALDH1A1 | |
| SCHEMBL17922579 | 0.76 | HSD11B1 (0.47) | L3MBTL1TSHRACHEALDH1A1KDM4E | |
| SCHEMBL475089 | 0.75 | ALDH1A1 (0.55) | L3MBTL1RAPGEF4TSHRACHEALDH1A1 | |
| SCHEMBL29468592 | 0.75 | ALDH1A1 (0.55) | L3MBTL1RAPGEF4TSHRACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101027295-A | Chemical compounds and pharmaceutical compositions containing them for the treatment of inflammatory disorders | SCHERING CORP (US) | 2007-08-29 | — | — | CN | disclosed |