SCHEMBL28292411

SCHEMBL28292411

CCC(c1ccc(O)c(CCl)c1)c1ccc(O)c(CCl)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.43
TYR P14679 2/20 0.43
ACHE P22303 2/20 0.43
CYP17A1 P05093 2/20 0.41
ALOX15 P16050 3/20 0.40
ALDH1A1 P00352 2/20 0.40
USP2 O75604 2/20 0.40
HPGD P15428 2/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 3/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
SHBG P04278 1/20 0.38
ADRB2 P07550 3/20 0.36
TSHR P16473 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
HIF1A Q16665 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2284641 0.85 ESR1 (0.48) BCHETYRACHECYP17A1ALOX15
SCHEMBL29508269 0.83 ADRB2 (0.51) BCHETYRACHECYP17A1PKM
SCHEMBL1986274 0.81 ALOX5 (0.46) BCHETYRACHECYP17A1ALOX15
SCHEMBL27983969 0.81 ALDH1A1 (0.52) TYRALOX15ALDH1A1USP2HPGD
SCHEMBL29664138 0.80 GABRA1 (0.58) BCHETYRACHECYP17A1ALOX15
SCHEMBL6246037 0.79 TYR (0.47) BCHETYRACHECYP17A1ALOX15
SCHEMBL3292528 0.79 ESR1 (0.46) BCHETYRACHECYP17A1ALOX15
SCHEMBL3934205 0.78 TDP1 (0.56) BCHETYRACHEALOX15ALDH1A1
SCHEMBL1960997 0.77 GABRA1 (0.56) BCHETYRACHECYP17A1ALDH1A1
SCHEMBL30002831 0.77 GABRA1 (0.56) BCHETYRACHECYP17A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715728-A Adduct and application thereof 亨斯迈先进材料美国有限责任公司 2019-05-03 CN disclosed