Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 18/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15880806 | 0.81 | CYP1A2 (0.50) | LNPEPMEN1KMT2A | |
| SCHEMBL28292630 | 0.80 | MEN1 (0.48) | LNPEPMEN1KMT2A | |
| SCHEMBL28941077 | 0.78 | MEN1 (0.41) | LNPEPMEN1KMT2A | |
| SCHEMBL28292573 | 0.78 | KIF11 (0.36) | LNPEPMEN1KMT2A | |
| SCHEMBL29064128 | 0.78 | NOS2 (0.62) | LNPEPMEN1KMT2A | |
| SCHEMBL28292605 | 0.77 | MEN1 (0.46) | LNPEPMEN1KMT2A | |
| SCHEMBL28817265 | 0.77 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL28940925 | 0.76 | CYP2D6 (0.46) | LNPEPMEN1KMT2A | |
| SCHEMBL29041391 | 0.75 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL28294334 | 0.75 | LOXL2 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |