Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292627 | 0.88 | SCN9A (0.41) | LOXL2SCN9AMEN1KMT2ARAF1 | |
| SCHEMBL28292621 | 0.82 | BRAF (0.46) | LOXL2MEN1KMT2ARAF1 | |
| SCHEMBL28940983 | 0.81 | SCN9A (0.40) | LOXL2SCN9ACFTRMEN1KMT2A | |
| SCHEMBL28963812 | 0.81 | SCN9A (0.40) | LOXL2SCN9ACFTRMEN1KMT2A | |
| SCHEMBL28292592 | 0.80 | KDR (0.53) | MEN1KMT2ARAF1KDR | |
| SCHEMBL28292577 | 0.80 | CCNC (0.48) | CNR2SCN9ACFTR | |
| SCHEMBL28940978 | 0.77 | SCN9A (0.39) | CNR2SCN9ACFTRCHRM1 | |
| SCHEMBL29262259 | 0.75 | MEN1 (0.48) | MEN1KMT2ARAF1KDR | |
| SCHEMBL28292551 | 0.75 | LNPEP (0.46) | MEN1KMT2A | |
| SCHEMBL28292634 | 0.75 | MEN1 (0.52) | MEN1KMT2ARAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |