Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 17/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 13/20 | 0.59 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.50 |
| ▸ | L3MBTL4 | Q8NA19 | 3/20 | 0.50 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298702 | 0.86 | POLB (0.54) | L3MBTL1KMT2APOLB | |
| SCHEMBL4042348 | 0.81 | KMT2A (0.57) | KMT2ASMN1; SMN2POLB | |
| SCHEMBL2321965 | 0.81 | ACHE (0.67) | KDM4EKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1920680 | 0.79 | ALDH1A1 (0.49) | L3MBTL1KDM4EKMT2ASMN1; SMN2POLB | |
| SCHEMBL28291402 | 0.78 | ACHE (0.46) | L3MBTL3L3MBTL1MBTD1L3MBTL4TP53BP1 | |
| SCHEMBL27991527 | 0.77 | L3MBTL3 (0.66) | L3MBTL3L3MBTL1 | |
| SCHEMBL15705466 | 0.77 | L3MBTL3 (0.74) | L3MBTL3L3MBTL1MBTD1L3MBTL4TP53BP1 | |
| SCHEMBL7428185 | 0.77 | MAPT (0.56) | L3MBTL3L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL8158995 | 0.76 | POLB (0.74) | L3MBTL3L3MBTL1MBTD1L3MBTL4TP53BP1 | |
| SCHEMBL13731378 | 0.76 | L3MBTL3 (0.72) | L3MBTL3L3MBTL1MBTD1L3MBTL4TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104350055-B | Bicyclic heteroaryl derivatives and application thereof as MNK1 and MNK2 regulator | 新加坡科技研究局 | 2019-05-31 | — | — | CN | disclosed |