Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30672032 | 0.78 | ALDH1A1 (0.40) | MEN1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL28293121 | 0.76 | CYP11B1 (0.34) | MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL28293129 | 0.73 | HTT (0.37) | TAAR1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28293143 | 0.73 | SLC1A3 (0.31) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28291573 | 0.68 | ALDH1A1 (0.40) | MEN1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL27666909 | 0.67 | — | — | |
| SCHEMBL28293137 | 0.66 | BRD4 (0.33) | — | |
| SCHEMBL27978505 | 0.66 | ACHE (0.40) | MEN1ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL28043766 | 0.65 | — | — | |
| SCHEMBL248034 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105324117-B | Polysubstituted aromatic compounds as serine protease inhibitors | 维颂公司 | 2019-04-09 | — | — | CN | claimed |