SCHEMBL28293143

SCHEMBL28293143

O=CC1C=CC=CN1Cc1ccoc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30672032 0.78 ALDH1A1 (0.40) MEN1KMT2A
SCHEMBL28293121 0.76 CYP11B1 (0.34) MEN1KMT2A
SCHEMBL28293105 0.73 TAAR1 (0.35) SLC1A3SLC1A2SLC1A1MEN1KMT2A
SCHEMBL28291573 0.73 ALDH1A1 (0.40) MEN1KMT2A
SCHEMBL28293129 0.71 HTT (0.37) MEN1KMT2A
SCHEMBL27666909 0.67
SCHEMBL28293137 0.66 BRD4 (0.33)
SCHEMBL27978505 0.66 ACHE (0.40) MEN1KMT2A
SCHEMBL28043766 0.65
SCHEMBL9306536 0.64 SIGMAR1 (0.34) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105324117-B Polysubstituted aromatic compounds as serine protease inhibitors 维颂公司 2019-04-09 CN claimed