Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | TRIP13 | Q15645 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30672032 | 0.84 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28872835 | 0.82 | CHRNB2 (0.41) | CYP11B1KDM4EALDH1A1HTTMEN1 | |
| SCHEMBL28293105 | 0.76 | TAAR1 (0.35) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28293143 | 0.76 | SLC1A3 (0.31) | MEN1KMT2A | |
| SCHEMBL28293137 | 0.74 | BRD4 (0.33) | BRD4 | |
| SCHEMBL28293129 | 0.73 | HTT (0.37) | KDM4EGBA1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28291573 | 0.70 | ALDH1A1 (0.40) | KDM4EGBA1ALDH1A1MEN1KMT2A | |
| SCHEMBL27666909 | 0.69 | — | — | |
| SCHEMBL27978505 | 0.68 | ACHE (0.40) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL28043766 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105324117-B | Polysubstituted aromatic compounds as serine protease inhibitors | 维颂公司 | 2019-04-09 | — | — | CN | claimed |