Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079176 | 0.88 | CCR2 (0.54) | CCR2ALDH1A1MAPTMAPK1F10 | |
| SCHEMBL28293100 | 0.73 | CCR2 (0.46) | CCR2ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL1653950 | 0.70 | CCR2 (0.46) | CCR2ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL7953990 | 0.70 | TSHR (0.46) | CCR2ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL26660685 | 0.68 | CCR2 (0.44) | CCR2ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7993476 | 0.67 | CCR2 (0.64) | CCR2ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL30418401 | 0.67 | CCR2 (0.42) | CCR2ALDH1A1MAPK1KDM4EL3MBTL1 | |
| SCHEMBL3560535 | 0.65 | NOD2 (0.48) | CCR2ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL18640132 | 0.65 | AKR1C4 (0.54) | ALDH1A1MAPTKDM4EPKML3MBTL1 | |
| SCHEMBL17865512 | 0.64 | XDH (0.58) | ALDH1A1MAPTKDM4EPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658625-B | Indole amide compounds as inhibitors of cellular necrosis | 株式会社LG化学 | 2019-05-03 | — | — | CN | disclosed |