Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730380 | 0.84 | L3MBTL1 (0.49) | LMNANPC1MEN1KMT2ATDP1 | |
| SCHEMBL3996879 | 0.81 | ALDH1A1 (0.48) | ACACBLMNAMEN1KMT2AACACA | |
| SCHEMBL6658096 | 0.80 | MAOB (0.57) | ACACBLMNACYP1A2PARP10 | |
| SCHEMBL9035427 | 0.77 | L3MBTL1 (0.50) | ACACBLMNANPC1MEN1KMT2A | |
| SCHEMBL4623899 | 0.77 | ESR1 (0.46) | LMNANPC1MEN1CYP1A2KMT2A | |
| SCHEMBL8660435 | 0.77 | POLB (0.42) | ACACBLMNAMEN1KMT2ATDP1 | |
| SCHEMBL5321358 | 0.77 | BRD4 (0.50) | LMNAMEN1CYP1A2KMT2APOLB | |
| SCHEMBL6935978 | 0.77 | STAT3 (0.46) | LMNAMEN1KMT2ATDP1CNR2 | |
| SCHEMBL3997124 | 0.76 | HTT (0.41) | LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL3700232 | 0.75 | LMNA (0.41) | LMNANPC1MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748785-A | Two aromatic hydrocarbon substituted propenone class compounds of one kind and preparation method and application | 山东大学 | 2019-05-14 | — | — | CN | disclosed |