Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293597 | 0.80 | ACACB (0.48) | ACACBPARP10LMNACYP1A2 | |
| SCHEMBL4729080 | 0.79 | ALDH1A1 (0.50) | LMNA | |
| SCHEMBL2023883 | 0.78 | LMNA (0.58) | MAOBALOX5NR4A1NR4A2NR4A3 | |
| SCHEMBL4730380 | 0.78 | L3MBTL1 (0.49) | FFAR1LMNA | |
| SCHEMBL27733432 | 0.78 | NR4A1 (0.57) | MAOBFFAR1ALOX5NR4A1NR4A2 | |
| SCHEMBL5390077 | 0.77 | ALOX5 (0.56) | MAOBFFAR1ALOX5NR4A1NR4A2 | |
| SCHEMBL3251101 | 0.77 | LTA4H (0.57) | MAOBFFAR1ALOX5NR4A1NR4A2 | |
| SCHEMBL20425306 | 0.77 | MAOB (0.70) | MAOBFFAR1ALOX5NR4A1NR4A2 | |
| SCHEMBL28045714 | 0.77 | MAOB (0.60) | MAOBFFAR1ALOX5NR4A1NR4A2 | |
| SCHEMBL8162876 | 0.77 | FFAR1 (0.67) | MAOBFFAR1ALOX5NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012663-A2 | HYDANTOIN DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-ALPHA CONVERTING ENZYME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-02-12 | — | — | WO | disclosed |