SCHEMBL28293969

SCHEMBL28293969

O=Cc1occc1C=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.42
ALDH1A1 P00352 5/20 0.41
CYP2A6 P11509 1/20 0.41
TRPA1 O75762 3/20 0.41
NFE2L2 Q16236 3/20 0.41
LMNA P02545 1/20 0.41
ALOX5 P09917 1/20 0.41
MAPK1 P28482 1/20 0.41
MAPT P10636 3/20 0.40
F2 P00734 1/20 0.40
DPYD Q12882 1/20 0.38
CHAT P28329 1/20 0.37
CYP19A1 P11511 1/20 0.36
MAOA P21397 1/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51408 0.75
Water SCHEMBL15210122 0.73 ALDH1A1 (0.41) MAOBALDH1A1CYP2A6LMNAMAOA
Water SCHEMBL3454746 0.73 ALDH1A1 (0.41) MAOBALDH1A1CYP2A6LMNAMAOA
SCHEMBL28562323 0.73 ALDH1A1 (0.41) MAOBALDH1A1CYP2A6LMNAMAOA
SCHEMBL18244971 0.73 TRPA1 (0.44) MAOBALDH1A1TRPA1NFE2L2LMNA
SCHEMBL18244972 0.73 TRPA1 (0.44) MAOBALDH1A1TRPA1NFE2L2LMNA
SCHEMBL11306795 0.72 ALDH1A1 (0.33) ALDH1A1
SCHEMBL24385991 0.71 LMNA (0.62) MAOBALDH1A1CYP2A6TRPA1NFE2L2
SCHEMBL192400 0.71 LMNA (0.62) MAOBALDH1A1CYP2A6TRPA1NFE2L2
SCHEMBL30958792 0.71 LMNA (0.62) MAOBALDH1A1CYP2A6TRPA1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796426-A A method of utilizing basic zeolite molecular sieve catalytic cortex cinnamomi acid decarboxylation coupling reaction 常州大学 2019-05-24 CN disclosed